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U.C. Berkeley Division of Biostatistics Working Paper Series

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Papers from 2008: Targeted Methods for Biomarker Discovery, the Search for a Standard (March 24, 2008) Catherine Tuglus and Mark J. van der Laan
Download PDF [1.6 MB] Summary; The Construction and Analysis of Adaptive Group Sequential Designs (March 20, 2008) Mark J. van der Laan
Download PDF [7.7 MB] Summary; Data-adaptive Selection Of The Adjustment Set In Variable Importance Estimation (March 12, 2008) Oliver Bembom, Jeffrey W. Fessel, Robert W. Shafer, and Mark J. van der Laan
Download PDF [982 K] Summary; Data-adaptive selection of the truncation level for Inverse-Probability-of-Treatment-Weighted estimators (March 12, 2008) Oliver Bembom and Mark J. van der Laan
Download PDF [796 K] Summary; Covariate Adjustment for the Intention-to-Treat Parameter with Empirical Efficiency Maximization (February 8, 2008) Daniel B. Rubin and Mark J. van der Laan
Download PDF [739 K] Summary; Using Regression Models to Analyze Randomized Trials: Asymptotically Valid Hypothesis Tests Despite Incorrectly Specified Models (January 11, 2008) Michael Rosenblum and Mark J. van der Laan
Download PDF [1.7 MB] Summary
Papers from 2007: Loss-Based Estimation with Evolutionary Algorithms and Cross-Validation (November 11, 2007) David Shilane, Richard H. Liang, and Sandrine Dudoit
Download PDF [1.3 MB] Summary; Resampling-Based Empirical Bayes Multiple Testing Procedures for Controlling Generalized Tail Probability and Expected Value Error Rates: (November 10, 2007) Sandrine Dudoit, Houston N. Gilbert, and Mark J. van der Laan
Download PDF [1.3 MB] Summary; A Note on Targeted Maximum Likelihood and Right Censored Data (October 18, 2007) Mark J. van der Laan and Daniel Rubin
Download PDF [433 K] Summary; Detailed Version: Analyzing Direct Effects in Randomized Trials with Secondary Interventions: An Application to HIV Prevention Trials (October 15, 2007) Michael A. Rosenblum, Nicholas P. Jewell, Mark J. van der Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian
Download PDF [1.2 MB] Summary; Analyzing Direct Effects in Randomized Trials with Secondary Interventions (September 15, 2007) Michael Rosenblum, Nicholas P. Jewell, Mark J. van der Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian
Download PDF [957 K] Summary; Time-Dependent Performance Comparison of Stochastic Optimization Algorithms (August 27, 2007) David Shilane, Jarno Martikainen, and Seppo Ovaska
Download PDF [5.3 MB] Summary; Biomarker Discovery Using Targeted Maximum Likelihood Estimation: Application to the Treatment of Antiretroviral Resistant HIV Infection (August 6, 2007) Oliver Bembom, Maya L. Petersen , Soo-Yon Rhee , W. Jeffrey Fessel , Sandra E. Sinisi, Robert W. Shafer, and Mark J. van der Laan
Download PDF [779 K] Summary; Empirical Efficiency Maximization (July 24, 2007) Daniel B. Rubin and Mark J. van der Laan
Download PDF [1.4 MB] Summary; Regression Analysis of a Disease Onset Distribution Using Diagnosis Data (July 12, 2007) Jessica G. Young, Nicholas P. Jewell, and Steven J. Samuels
Download PDF [965 K] Summary; Super Learner (July 7, 2007) Mark J. van der Laan, Eric C. Polley, and Alan E. Hubbard
Download PDF [783 K] Summary; Estimating the Effect of Vigorous Physical Activity on Mortality in the Elderly Based on Realistic Individualized Treatment and Intention-to-Treat Rules (May 11, 2007) Oliver Bembom and Mark J. van der Laan
Download PDF [655 K] Summary; Analyzing Sequentially Randomized Trials Based on Causal Effect Models for Realistic Individualized Treatment Rules (May 10, 2007) Oliver Bembom and Mark J. van der Laan
Download PDF [904 K] Summary; Covariate Adjustment in Randomized Trials with Binary Outcomes: Targeted Maximum Likelihood Estimation (April 11, 2007) Kelly L. Moore and Mark J. van der Laan
Download PDF [1.0 MB] Summary; The Causal Effect of Recent Leisure-Time Physical Activity on All-Cause Mortality Among the Elderly (February 1, 2007) Oliver Bembom, Mark J. van der Laan, and Ira B. Tager
Download PDF [1.8 MB] Summary
Papers from 2006: Targeted Maximum Likelihood Learning (October 6, 2006) Mark J. van der Laan and Daniel Rubin
Download PDF [3.0 MB] Summary; Extending Marginal Structural Models through Local, Penalized, and Additive Learning (September 11, 2006) Daniel Rubin and Mark J. van der Laan
Download PDF [758 K] Summary; Diagnosing Bias in the Inverse Probability of Treatment Weighted Estimator Resulting from Violation of Experimental Treatment Assignment (September 11, 2006) Yue Wang, Maya L. Petersen, David Bangsberg, and Mark J. van der Laan
Download PDF [917 K] Summary; Statistical Learning of Origin-Specific Statically Optimal Individualized Treatment Rules (September 1, 2006) Mark J. van der Laan and Maya L. Petersen
Download PDF [1.2 MB] Summary; Supervised Detection of Conserved Motifs in DNA Sequences with cosmo (July 26, 2006) Oliver Bembom, Sunduz Keles, and Mark J. van der Laan
Download PDF [2.3 MB] Summary; Doubly Robust Censoring Unbiased Transformations (June 14, 2006) Daniel Rubin and Mark J. van der Laan
Download PDF [1.3 MB] Summary; A Method to Increase the Power of Multiple Testing Procedures Through Sample Splitting (June 2, 2006) Daniel Rubin, Sandrine Dudoit, and Mark J. van der Laan
Download PDF [737 K] Summary; Individualized Treatment Rules: Generating Candidate Clinical Trials (May 26, 2006) Maya L. Petersen, Steven G. Deeks, and Mark J. van der Laan
Download PDF [1.6 MB] Summary; Super Learning: An Application to Prediction of HIV-1 Drug Susceptibility (April 13, 2006) Sandra E. Sinisi, Maya L. Petersen, and Mark J. van der Laan
Download PDF [792 K] Summary; Empirical Bayes Approach to Controlling Familywise Error: An Application to HIV Resistance Data (April 12, 2006) Rhoderick N. Machekano and Alan E. Hubbard
Download PDF [863 K] Summary; Causal Effect Models for Intention to Treat and Realistic Individualized Treatment Rules (March 30, 2006) Mark J. van der Laan
Download PDF [1.5 MB] Summary; A General Framework for Statistical Performance Comparison of Evolutionary Computation Algorithms (March 16, 2006) David Shilane, Jarno Martikainen, Sandrine Dudoit, and Seppo Ovaska
Download PDF [675 K] Summary; Multiple Tests of Association with Biological Annotation Metadata (March 1, 2006) Sandrine Dudoit, Sunduz Keles, and Mark J. van der Laan
Download PDF [3.3 MB] Summary
Papers from 2005: History-Adjusted Marginal Structural Models to Estimate Time-Varying Effect Modification (December 2, 2005) Maya L. Petersen, Steven G. Deeks, Jeffrey N. Martin, and Mark J. van der Laan
Download PDF [888 K] Summary; Issues of Processing and Multiple Testing of SELDI-TOF MS Proteomic Data (December 1, 2005) Merrill D. Birkner, Alan E. Hubbard, Mark J. van der Laan, Christine F. Skibola, Christine M. Hegedus, and Martyn T. Smith
Download PDF [604 K] Summary; Quantile-Function Based Null Distribution in Resampling Based Multiple Testing (November 30, 2005) Mark J. van der Laan and Alan E. Hubbard
Download PDF [1.2 MB] Summary; Data Adaptive Pathway Testing (November 29, 2005) Merrill D. Birkner, Alan E. Hubbard, and Mark J. van der Laan
Download PDF [788 K] Summary; Application of a Variable Importance Measure Method to HIV-1 Sequence Data (November 16, 2005) Merrill D. Birkner and Mark J. van der Laan
Download PDF [628 K] Summary; Correspondences between Regression Models for Complex Binary Outcomes and Those for Structured Multivariate Survival Analyses (November 16, 2005) Nicholas P. Jewell
Download PDF [732 K] Summary; A General Imputation Methodology for Nonparametric Regression with Censored Data (November 14, 2005) Dan Rubin and Mark J. van der Laan
Download PDF [1.5 MB] Summary; Efficacy Studies of Malaria Treatments in Africa: Efficient Estimation with Missing Indicators of Failure (November 1, 2005) Rhoderick N. Machekano, Grant Dorsey, and Alan E. Hubbard
Download PDF [919 K] Summary; A Fine-Scale Linkage Disequilibrium Measure Based on Length of Haplotype Sharing (October 20, 2005) Yan Wang, Lue Ping Zhao, and Sandrine Dudoit
Download PDF [3.3 MB] Summary; Population Intervention Models in Causal Inference (October 13, 2005) Alan E. Hubbard and Mark J. van der Laan
Download PDF [1.5 MB] Summary; Estimation of Direct Causal Effects (September 22, 2005) Maya L. Petersen and Mark J. van der Laan
Download PDF [957 K] Summary; Cross-validated Bagged Prediction of Survival (September 9, 2005) Sandra E. Sinisi, Romain Neugebauer, and Mark J. van der Laan
Download PDF [1.6 MB] Summary; Statistical Inference for Variable Importance (August 25, 2005) Mark J. van der Laan
Download PDF [1.3 MB] Summary; Direct Effect Models (August 25, 2005) Mark J. van der Laan and Maya L. Petersen
Download PDF [1.2 MB] Summary; Survival Point Estimate Prediction in Matched and Non-Matched Case-Control Subsample Designed Studies (August 19, 2005) Annette M. Molinaro, Mark J. van der Laan, Dan H. Moore, and Karla Kerlikowske
Download PDF [1.1 MB] Summary; Application of a Multiple Testing Procedure Controlling the Proportion of False Positives to Protein and Bacterial Data (August 8, 2005) Merrill D. Birkner, Alan E. Hubbard, and Mark J. van der Laan
Download PDF [789 K] Summary; Cross-Validating and Bagging Partitioning Algorithms with Variable Importance (August 5, 2005) Annette M. Molinaro and Mark J. van der Laan
Download PDF [920 K] Summary; Test Statistics Null Distributions in Multiple Testing: Simulation Studies and Applications to Genomics (July 28, 2005) Katherine S. Pollard, Merrill D. Birkner, Mark J. van der Laan, and Sandrine Dudoit
Download PDF [1.9 MB] Summary; G-computation Estimation of Nonparametric Causal Effects on Time-Dependent Mean Outcomes in Longitudinal Studies (July 5, 2005) Romain Neugebauer and Mark J. van der Laan
Download PDF [1.6 MB] Summary; Cross-validated Bagged Learning (June 28, 2005) Mark J. van der Laan, Sandra E. Sinisi, and Maya L. Petersen
Download PDF [1.4 MB] Summary; A Note on the Construction of Counterfactuals and the G-computation Formula (June 28, 2005) Zhuo Yu and Mark J. van der Laan
Download PDF [641 K] Summary; Estimating Function Based Cross-Validation and Learning (May 19, 2005) Mark J. van der Laan and Daniel Rubin
Download PDF [1.6 MB] Summary; Prognosis of Stage II Colon Cancer by Non-Neoplastic Mucosa Gene Expresssion Profiling (May 16, 2005) Alain Barrier, Sandrine Dudoit, and et al.
Download PDF [889 K] Summary; Colon Cancer Prognosis Prediction by Gene Expression Profiling (May 16, 2005) Alain Barrier, Sandrine Dudoit, and et al.
Download PDF [1.1 MB] Summary; Causal Inference in Longitudinal Studies with History-Restricted Marginal Structural Models (April 11, 2005) Romain Neugebauer, Mark J. van der Laan, and Ira B. Tager
Download PDF [913 K] Summary; History-Adjusted Marginal Structural Models: Optimal Treatment Strategies (April 5, 2005) Maya L. Petersen and Mark J. van der Laan
Download PDF [459 K] Summary; Survival Ensembles (April 5, 2005) Torsten Hothorn, Peter Buhlmann, Sandrine Dudoit, Annette M. Molinaro, and Mark J. van der Laan
Download PDF [1.4 MB] Summary; History-Adjusted Marginal Structural Models: Time-Varying Effect Modification (April 5, 2005) Maya L. Petersen and Mark J. van der Laan
Download PDF [494 K] Summary; Nonparametric Estimation of the Case Fatality Ratio with Competing Risks Data: An Application to Severe Acute Respiratory Syndome (SARS) (April 1, 2005) Nicholas P. Jewell, Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, and A. J. Hedley
Download PDF [1004 K] Summary; Resampling Based Multiple Testing Procedure Controlling Tail Probability of the Proportion of False Positives (March 30, 2005) Mark J. van der Laan, Merrill D. Birkner, and Alan E. Hubbard
Download PDF [1.1 MB] Summary; Optimization of the Architecture of Neural Networks Using a Deletion/Substitution/Addition Algorithm (March 15, 2005) Blythe Durbin, Sandrine Dudoit, and Mark J. van der Laan
Download PDF [1.3 MB] Summary; A Causal Inference Approach for Constructing Transcriptional Regulatory Networks (March 4, 2005) Biao Xing and Mark J. van der Laan
Download PDF [1.1 MB] Summary; Multiple Testing Procedures and Applications to Genomics (January 5, 2005) Merrill D. Birkner, Katherine S. Pollard, Mark J. van der Laan, and Sandrine Dudoit
Download PDF [1.3 MB] Summary; Cluster Analysis of Genomic Data with Applications in R (January 5, 2005) Katherine S. Pollard and Mark J. van der Laan
Download PDF [1.3 MB] Summary
Papers from 2004: Multiple Testing Procedures for Controlling Tail Probability Error Rates (December 15, 2004) Sandrine Dudoit, Mark J. van der Laan, and Merrill D. Birkner
Download PDF [2.7 MB] Summary; Multiple Testing Procedures: R multtest Package and Applications to Genomics (December 9, 2004) Katherine S. Pollard, Sandrine Dudoit, and Mark J. van der Laan
Download PDF [1.7 MB] Summary; Choice of Monitoring Mechanism for Optimal Nonparametric Functional Estimation for Binary Data (November 16, 2004) Nicholas P. Jewell, Mark J. van der Laan, and Stephen Shiboski
Download PDF [409 K] Summary; Deletion/Substitution/Addition Algorithm for Partitioning the Covariate Space in Prediction (November 9, 2004) Annette Molinaro and Mark J. van der Laan
Download PDF [2.4 MB] Summary; Multiple Testing and Data Adaptive Regression: An Application to HIV-1 Sequence Data (October 26, 2004) Merrill D. Birkner, Sandra E. Sinisi, and Mark J. van der Laan
Download PDF [930 K] Summary; GLLAMM Manual (October 25, 2004) Sophia Rabe-Hesketh, Anders Skrondal, and Andrew Pickles
Download PDF [4.7 MB] Summary; Data Adaptive Estimation of the Treatment Specific Mean (October 20, 2004) Yue Wang, Oliver Bembom, and Mark J. van der Laan
Download PDF [1.3 MB] Summary; History-Adjusted Marginal Structural Models and Statically-Optimal Dynamic Treatment Regimes (September 24, 2004) Mark J. van der Laan and Maya L. Petersen
Download PDF [460 K] Summary; Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome (September 2, 2004) Mark J. van der Laan, Alan E. Hubbard, and Nicholas P. Jewell
Download PDF [1.3 MB] Summary; Estimating a Survival Distribution with Current Status Data and High-Dimensional Covariates (September 2, 2004) Mark J. van der Laan and Aad van der Vaart
Download PDF [1.2 MB] Summary; Estimation of Direct and Indirect Causal Effects in Longitudinal Studies (August 23, 2004) Mark J. van der Laan and Maya L. Petersen
Download PDF [1.1 MB] Summary; Linear Life Expectancy Regression with Censored Data (August 1, 2004) Ying Qing Chen and Su-Chun Cheng
Download PDF [1.2 MB] Summary; A Note on Empirical Likelihood Inference of Residual Life Regression (July 8, 2004) Ying Qing Chen and Yichuan Zhao
Download PDF [350 K] Summary; Semiparametric Quantitative-Trait-Locus Mapping: II. on Censored Age-at-Onset (July 1, 2004) Ying Qing Chen, Chengcheng Hu, and Rongling Wu
Download PDF [928 K] Summary; Semiparametric Quantitative-Trait-Locus Mapping: I. on Functional Growth Curves (July 1, 2004) Ying Qing Chen and Rongling Wu
Download PDF [804 K] Summary; Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks (June 29, 2004) Yan Wang and Sandrine Dudoit
Download PDF [2.3 MB] Summary; Mean Response Models of Repeated Measurements in Presence of Varying Effectiveness Onset (June 9, 2004) Ying Qing Chen and Su-Chun Cheng
Download PDF [857 K] Summary; Multiple Testing Methods For ChIP-Chip High Density Oligonucleotide Array Data (June 7, 2004) Sunduz Keles, Mark J. van der Laan, Sandrine Dudoit, and Simon E. Cawley
Download PDF [3.0 MB] Summary; Semiparametric Regression Analysis of Mean Residual Life with Censored Survival Data (May 27, 2004) Ying Qing Chen and Su-Chun Cheng
Download PDF [671 K] Summary; Regulatory Motif Finding by Logic Regression (March 30, 2004) Sunduz Keles, Mark J. van der Laan, and Chris Vulpe
Download PDF [1.3 MB] Summary; A Statistical Method for Constructing Transcriptional Regulatory Networks Using Gene Expression and Sequence Data (March 19, 2004) Biao Xing and Mark J. van der Laan
Download PDF [1.2 MB] Summary; Loss-Based Cross-Validated Deletion/Substitution/Addition Algorithms in Estimation (March 3, 2004) Sandra E. Sinisi and Mark J. van der Laan
Download PDF [1.9 MB] Summary; The Cross-Validated Adaptive Epsilon-Net Estimator (February 26, 2004) Mark J. van der Laan, Sandrine Dudoit, and Aad W. van der Vaart
Download PDF [1.6 MB] Summary; Multiple Testing. Part III. Procedures for Control of the Generalized Family-Wise Error Rate and Proportion of False Positives (January 1, 2004) Mark J. van der Laan, Sandrine Dudoit, and Katherine S. Pollard
Download PDF [941 K] Summary
Papers from 2003: Comparison of the Inverse Probability of Treatment Weighted (IPTW) Estimator With a Naïve Estimator in the Analysis of Longitudinal Data With Time-Dependent Confounding: A Simulation Study (December 17, 2003) Thaddeus Haight, Romain Neugebauer, Ira B. Tager, and Mark J. van der Laan
Download PDF [1.6 MB] Summary; Multiple Testing. Part II. Step-Down Procedures for Control of the Family-Wise Error Rate (December 16, 2003) Mark J. van der Laan, Sandrine Dudoit, and Katherine S. Pollard
Download PDF [1.3 MB] Summary; Multiple Testing. Part I. Single-Step Procedures for Control of General Type I Error Rates (December 15, 2003) Sandrine Dudoit, Mark J. van der Laan, and Katherine S. Pollard
Download PDF [2.4 MB] Summary; Loss-Based Estimation with Cross-Validation: Applications to Microarray Data Analysis and Motif Finding (December 5, 2003) Sandrine Dudoit, Mark J. van der Laan, Sunduz Keles, Annette M. Molinaro, Sandra E. Sinisi, and Siew Leng Teng
Download PDF [1.8 MB] Summary; Unified Cross-Validation Methodology For Selection Among Estimators and a General Cross-Validated Adaptive Epsilon-Net Estimator: Finite Sample Oracle Inequalities and Examples (November 26, 2003) Mark J. van der Laan and Sandrine Dudoit
Download PDF [3.6 MB] Summary; Measuring Treatment Effects Using Semiparametric Models (September 18, 2003) Zhuo Yu and Mark J. van der Laan
Download PDF [603 K] Summary; Asymptotically Optimal Model Selection Method with Right Censored Outcomes (September 4, 2003) Sunduz Keles, Mark J. van der Laan, and Sandrine Dudoit
Download PDF [1.1 MB] Summary; Tree-based Multivariate Regression and Density Estimation with Right-Censored Data (September 2, 2003) Annette M. Molinaro, Sandrine Dudoit, and Mark J. van der Laan
Download PDF [1.8 MB] Summary; Locally Efficient Estimation of Nonparametric Causal Effects on Mean Outcomes in Longitudinal Studies (July 25, 2003) Romain Neugebauer and Mark J. van der Laan
Download PDF [956 K] Summary; Resampling-based Multiple Testing: Asymptotic Control of Type I Error and Applications to Gene Expression Data (June 24, 2003) Katherine S. Pollard and Mark J. van der Laan
Download PDF [1.5 MB] Summary; Temporal Stability and Geographic Variation in Cumulative Case Fatality Rates and Average Doubling Times of SARS Epidemics (June 13, 2003) Alison P. Galvani, Xiudong Lei, and Nicholas P. Jewell
Download PDF [617 K] Summary; Double Robust Estimation in Longitudinal Marginal Structural Models (June 4, 2003) Zhuo Yu and Mark J. van der Laan
Download PDF [927 K] Summary; Supervised Detection of Regulatory Motifs in DNA Sequences (May 23, 2003) Sunduz Keles, Mark J. van der Laan, Sandrine Dudoit, Biao Xing, and Michael B. Eisen
Download PDF [1.3 MB] Summary; A Semiparametric Model Selection Criterion with Applications to the Marginal Structural Model (March 7, 2003) M. Alan Brookhart and Mark J. van der Laan
Download PDF [1.1 MB] Summary; IBD Configuration Transition Matrices and Linkage Score Tests for Unilineal Relative Pairs (February 14, 2003) Sandrine Dudoit
Download PDF [1.7 MB] Summary; Rank Regression in Stability Analysis (February 10, 2003) Ying Qing Chen, Annpey Pong, and Biao Xing
Download PDF [788 K] Summary; Asymptotics of Cross-Validated Risk Estimation in Estimator Selection and Performance Assessment (February 5, 2003) Sandrine Dudoit and Mark J. van der Laan
Download PDF [1.6 MB] Summary; Asymptotic Optimality of Likelihood Based Cross-Validation (February 5, 2003) Mark J. van der Laan, Sandrine Dudoit, and Sunduz Keles
Download PDF [869 K] Summary
Papers from 2002: Recurrent Events Analysis in the Presence of Time Dependent Covariates and Dependent Censoring (December 6, 2002) Maja Miloslavsky, Sunduz Keles, Mark J. van der Laan, and Steve Butler
Download PDF [941 K] Summary; Construction of Counterfactuals and the G-computation Formula (December 5, 2002) Zhuo Yu and Mark J. van der Laan
Download PDF [606 K] Summary; Analysis of Longitudinal Marginal Structural Models (November 27, 2002) Jennifer F. Bryan, Zhuo Yu, and Mark J. van der Laan
Download PDF [1.0 MB] Summary; Locally Efficient Estimation with Bivariate Right Censored Data (October 30, 2002) Christopher M. Quale, Mark J. van der Laan, and James M. Robins
Download PDF [1.3 MB] Summary; An Empirical Study of Marginal Structural Models for Time-Independent Treatment (October 21, 2002) Tanya A. Henneman and Mark J. van der Laan
Download PDF [578 K] Summary; Accelerated Hazards Model: Method, Theory and Applications (September 27, 2002) Ying Qing Chen, Nicholas P. Jewell, and Jingrong Yang
Download PDF [625 K] Summary; Locally Efficient Estimation of Regression Parameters Using Current Status Data (September 24, 2002) Chris Andrews, Mark J. van der Laan, and James M. Robins
Download PDF [900 K] Summary; Case-Control Current Status Data (September 23, 2002) Nicholas P. Jewell and Mark J. van der Laan
Download PDF [745 K] Summary; Why Prefer Double Robust Estimates? Illustration with Causal Point Treatment Studies (September 6, 2002) Romain Neugebauer and Mark J. van der Laan
Download PDF [1.2 MB] Summary; Bivariate Current Status Data (September 4, 2002) Mark J. van der Laan and Nicholas P. Jewell
Download PDF [618 K] Summary; Current Status Data: Review, Recent Developments and Open Problems (September 4, 2002) Nicholas P. Jewell and Mark J. van der Laan
Download PDF [1.2 MB] Summary; Semiparametric Regression Analysis on Longitudinal Pattern of Recurrent Gap Times (August 30, 2002) Ying Qing Chen, Mei-Cheng Wang, and Yijian Huang
Download PDF [737 K] Summary; Multiple Hypothesis Testing in Microarray Experiments (August 16, 2002) Sandrine Dudoit, Juliet Popper Shaffer, and Jennifer C. Boldrick
Download PDF [17.2 MB] Summary; Estimation of the Bivariate Survival Function with Generalized Bivariate Right Censored Data Structures (August 13, 2002) Sunduz Keles, Mark J. van der Laan, and James M. Robins
Download PDF [1.3 MB] Summary; Inference for Proportional Mean Residual Life Model in the Presence of Censoring (May 1, 2002) Ying Q. Chen and Nicholas P. Jewell
Download PDF [830 K] Summary; A Method to Identify Significant Clusters in Gene Expression Data (April 1, 2002) Katherine S. Pollard and Mark J. van der Laan
Download PDF [613 K] Summary; Comparative Genomic Hybridization Array Analysis (April 1, 2002) Annette M. Molinaro, Mark J. van der Laan, and Dan H. Moore
Download PDF [1.9 MB] Summary; A New Partitioning Around Medoids Algorithm (February 1, 2002) Mark J. van der Laan, Katherine S. Pollard, and Jennifer Bryan
Download PDF [5.2 MB] Summary; Estimating Causal Parameters in Marginal Structural Models with Unmeasured Confounders Using Instrumental Variables (January 1, 2002) Tanya A. Henneman, Mark Johannes van der Laan, and Alan E. Hubbard
Download PDF [731 K] Summary; Regression Analysis of Recurrent Gap Times with Time-Dependent Covariates (January 1, 2002) Ying Qing Chen, Mei-Cheng Wang, and Yijian Huang
Download PDF [968 K] Summary
Papers from 2001: Detection of Progressive Deterioration in Early Onset Schizophrenia with a New Statistical Method (December 1, 2001) Ying Qing Chen, Mei-Cheng Wang, and William W. Eaton
Download PDF [695 K] Summary; Marginal Regression of Gaps Between Recurrent Events (November 1, 2001) Yijian Huang and Ying Qing Chen
Download PDF [688 K] Summary; Maximum Likelihood Estimation of Ordered Multinomial Parameters (October 1, 2001) Nicholas P. Jewell and John D. Kalbfleisch
Download PDF [848 K] Summary; Locally Efficient Estimation with Bivariate Right Censored Data (October 1, 2001) Christopher M. Quale, Mark J. van der Laan, and James M. Robins
Summary; Identification of Regulatory Elements Using A Feature Selection Method (September 1, 2001) Sunduz Keles, Mark J. van der Laan, and Michael B. Eisen
Download PDF [719 K] Summary; Nonparametric Estimation from Current Status Data with Competing Risks (July 1, 2001) Nicholas P. Jewell, Mark J. van der Laan, and Tanya Henneman
Summary; Statistical Inference for Simultaneous Clustering of Gene Expression Data (July 1, 2001) Katherine S. Pollard and Mark J. van der Laan
Download PDF [496 K] Summary; Paired and Unpaired Comparisons and Clustering with Gene Expression Data (June 1, 2001) Jennifer F. Bryan, Katherine S. Pollard, and Mark J. van der Laan
Summary; Hybrid Clustering of Gene Expression Data with Visualization and the Bootstrap (May 1, 2001) Mark J. van der Laan and Katherine S. Pollard
Summary; Current Status and Right-Censored Data Structures When Observing a Marker at the Censoring Time (March 1, 2001) Mark J. van der Laan and Nicholas P. Jewell
Summary; Smooth Estimation of a Monotone Density (March 1, 2001) Aad W. van der Vaart and Mark J. van der Laan
Summary; Smooth Hazard Function Estimation for Interval Censored Data with Time Varying Covariates (February 1, 2001) Christopher Quale and Peter Bacchetti
Summary; Fitting of Mixtures with Unspecified Number of Components Using Cross Validation Distance Estimate (February 1, 2001) Maja Miloslavsky and Mark J. van der Laan
Summary; Mixture Hazards Models with Additive Random Effects Accounting for Treatment Effectiveness Lag Time (January 1, 2001) Ying Qing Chen, C. A. Rohde, and M.-C. Wang
Download PDF [1.0 MB] Summary
Papers from 2000: A Class of Semiparametric Scale-Change Hazards Regression Models and Its Adequacy for Censored Survival Data (October 1, 2000) Ying Qing Chen
Download PDF [1.2 MB] Summary; Gene Expression Analysis with the Parametric Bootstrap (June 1, 2000) Mark J. van der Laan and Jennifer F. Bryan
Summary; Locally Efficient Estimation in Censored Data Models: Theory and Examples (March 1, 2000) Mark J. van der Laan, Richard D. Gill, and James M. Robins
Summary; On a General Class of Semiparametric Hazards Regression Models (February 1, 2000) Ying Qing Chen and Nicholas P. Jewell
Summary; Locally Efficient Estimation of a Multivariate Survival Function in Longitudinal Studies (February 1, 2000) Mark J. van der Laan, Alan E. Hubbard, and James M. Robins
Summary
Papers from 1999: Assessing Adequacy of the Semiparametric Scale Change Hazards Regression Models (November 1, 1999) Ying Qing Chen
Summary; Estimating a Treatment Effect by the Accelerated Hazards Model (October 1, 1999) Ying Qing Chen and Mei-Cheng Wang
Summary; Analysis of Accelerated Hazards Models (October 1, 1999) Ying Qing Chen and Mei-Cheng Wang
Summary; The NPMLE in the Uniform Doubly Censored Current Status Data Model (August 1, 1999) Mark J. van der Laan and Nicholas P. Jewell
Summary
Papers from 1998: Nonparametric Efficient Estimation with Current Status Data and Right-Censored Data Structures When Observing a Marker at the Censoring Time (October 1, 1998) Mark J. van der Laan and Nicholas P. Jewell
Summary; Estimation with Interval Censored Data in Longitudinal Studies (September 1, 1998) Mark J. van der Laan
Summary; The Nonparametric Maximum Likelihood Estimator in a Class of Doubly Censored Current Status Data Models with Application to Partner Studies (September 1, 1998) Mark J. van der Laan and Chris Andrews
Summary; Subset Selection in Explanatory Regression Analyses (April 1, 1998) Derick R. Peterson and Richard J. Brand
Summary; Automating Data Entry and Validation in Clinical Research (April 1, 1998) Andrew D. Graham, Robert E. Fusaro, and Kenneth A. Polse
Summary; Subset Selection Based on Order Statistics from Logistic Populations (March 1, 1998) Mark J. van der Laan and Paul van der Laan
Summary; Inference with Bivariate Truncated Data (February 1, 1998) Christopher M. Quale and Mark J. van der Laan
Summary; Nonparametric Locally Efficient Estimation of the Treatment Specific Survival Distribution with Right Censored Data and Covariates in Observational Studies (January 1, 1998) Alan E. Hubbard, Mark J. van der Laan, and James M. Robins
Summary; Locally Efficient Estimation of the Quality Adjusted Lifetime Distribution with Right-Censored Data and Covariates (January 1, 1998) Mark J. van der Laan and Alan E. Hubbard
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Papers from 1997: Efficient Estimation from Right-Censored Data When Failure Indicators are Missing at Random (August 1, 1997) Mark J. van der Laan and Ian W. McKeague
Summary; Efficient Estimation of the Lifetime and Disease Onset Distribution (August 1, 1997) Mark J. van der Laan, Nicholas P. Jewell, and Derick R. Peterson
Summary; Smooth Estimation and Inference with Interval Censored Data (July 1, 1997) Mark J. van der Laan and Derick R. Peterson
Summary; Locally Efficient Estimation of the Survival Distribution with Right Censored Data and Covariates When Collection of Data is Delayed (May 1, 1997) Mark J. van der Laan and Alan E. Hubbard
Summary; Locally Efficient Estimation with Current Status Data and Time-Dependent Covariates (May 1, 1997) Mark J. van der Laan and James M. Robins
Summary
Papers from 1996: Estimation with Interval Censored Data and Covariates (April 1, 1996) Mark J. van der Laan and Alan E. Hubbard
Summary; Singly and Doubly Censored Current Status Data With Extensions to Multi-State Counting Processes (April 1, 1996) Nicholas P. Jewell and Mark J. van der Laan
Summary; Backcalculation of Multiple Sclerosis Incidence Rates Based on Faroe Islands Data (February 1, 1996) Nicholas P. Jewell and Biao Wm. Lu
Summary
Papers from 1995: Locally Efficient Estimation with Current Status Data and High Dimensional Covariates (September 1, 1995) Mark J. van der Laan
Summary; The Two-Interval Line-Segment Problem (September 1, 1995) Mark J. van der Laan
Summary; Efficiency of the Sieved-NPMLE in CAR-Missing Data Models (June 1, 1995) Mark J. van der Laan
Summary; Nonparametric Estimation of the Bivariate Survival Function with Truncated Data (April 1, 1995) Mark J. van der Laan
Summary; A Modification of the Re-Distribution to the Right Algorithm Using Disease Markers (March 1, 1995) Hina M. Malani
Summary
Papers from 1994: Singly and Doubly Censored Current Status Data: Estimation, Asymptotics and Regression (November 1, 1994) Mark J. van der Laan, Peter J. Bickel, and Nicholas P. Jewell
Summary; Efficient and Ad Hoc Estimation in the Bivariate Censoring Model (September 1, 1994) Mark J. van der Laan
Summary; Generalizations of Current Status Data With Applications (August 1, 1994) Nicholas P. Jewell and Mark J. van der Laan
Summary; Simulation Properties of Malani's Modified Kaplan-Meier Estimator (August 1, 1994) Sandra R. Percell and Hina M. Malani
Summary; Semi-Parametric Estimation of the Mean Trajectory of a Marker Using Data from a Prevalent Cohort (July 1, 1994) Eric Vittinghoff, Hina M. Malani, and Nicholas P. Jewell
Summary; Regression with Doubly Censored Current Status Data (July 1, 1994) Daniel Rabinowitz and Nicholas P. Jewell
Summary; Proving Efficiency of NPMLE and Identities (April 1, 1994) Mark J. van der Laan
Summary; Double Censoring and All That: Problems in Biostatistical Inference (January 1, 1994) Nicholas P. Jewell
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Papers from 1993: Non-Parametric Estimation and Doubly-Censored Data: General Ideas and Applications to AIDS (August 1, 1993) Nicholas P. Jewell
Summary; Shaping the Future of Public Health: The Role of Biostatistics (July 1, 1993) Nicholas P. Jewell
Summary; A Competing Risks Analysis of Presenting AIDS Diagnoses Trends (April 1, 1993) Robert E. Fusaro, Peter Bacchetti, and Nicholas P. Jewell
Summary; A Markov Chain Monte Carlo Approach to the Nonlinear Mixed Model for Repeated Measures Data (March 1, 1993) Jack Gerson, Richard J. Brand, and Jonathan Raz
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Papers from 1992: Nonparametric Estimation for a Form of Doubly Censored Data, with Application to Two Problems in AIDS (November 1, 1992) Nicholas P. Jewell, Hina M. Malani, and Eric Vittinghoff
Summary; Estimating Multiple Tumor Transition Rates Based on Data from Survival/Sacrifice Experiments (September 1, 1992) Ying Lu and Hina M. Malani
Summary; Generation of Simplex Lattice Points (August 1, 1992) Scott Chasalow and Richard Brand
Summary; Variances for Maximum Penalized Likelihood Estimates Obtained via the EM Algorithm (August 1, 1992) Mark R. Segal, Peter Bacchetti, and Nicholas P. Jewell
Summary; Backcalculation of HIV Infection Rates (July 1, 1992) Peter Bacchetti, Mark R. Segal, and Nicholas P. Jewell
Summary; Markers Models in Survival Analysis and Applications to Issues Associated with AIDS (April 1, 1992) Nicholas P. Jewell and John D. Kalbfleisch
Summary; Uncertainty About the Incubation Period of AIDS and its Impact on Backcalculation (April 1, 1992) Peter R. Bacchetti, Mark R. Segal, and Nicholas P. Jewell
Summary; A Note on the Asymptotic Variance of Survival Function in the Semi-Markov Model (April 1, 1992) Hina M. Malani, Jens Nielsen, and William J. Redfearn
Summary; Estimating Patterns of CD4+ Lymphocyte Decline Using Data from a Prevalent Cohort of HIV Infected Individuals (January 1, 1992) Eric Vittinghoff, Hina M. Malani, and Nicholas P. Jewell
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Papers from 1991: The Design and Analysis of Partner Studies of HIV Transmission (December 2, 1991) Nicholas P. Jewell and Stephen C. Shiboski
Summary; A Geometric Approach to Assess Bias Due to Omitted Covariates in Generalized Linear Models (November 1, 1991) John M. Neuhaus and Nicholas P. Jewell
Summary; The Impact of Uncertainty in the AIDS Incubation Period on Reconstructions of the HIV Epidemic (November 1, 1991) Peter Bacchetti, Mark R. Segal, and Nicholas P. Jewell
Summary; An Annotated Bibliography of Methods for Analyzing Correlated Categorical Data (June 1, 1991) Mark Ashby, John M. Neuhaus, Walter W. Hauck, Peter Bacchetti, David C. Heilbron, Nicholas P. Jewell, Mark R. Segal, and Robert E. Fusaro
Summary; Marker Processes in Survival Analysis (May 1, 1991) Nicholas P. Jewell and John D. Kalbfleisch
Summary; Comparing the Positive Jackknife with the Usual Jackknife (May 1, 1991) Nicholas P. Jewell
Summary; A Framework for Consistent Prediction Rules Based on Markers (May 1, 1991) Jens Perch Nielsen and Nicholas P. Jewell
Summary; Marker-Dependent Hazard Estimation: An Application to AIDS (May 1, 1991) Robert E. Fusaro, Jens P. Nielsen, and Thomas H. Scheike
Summary; Distance and Risk Measures for the Analysis of Spatial Data: A Study of Childhood Cancers (January 1, 1991) Steve Selvin, Jane Schulman, and Deane W. Merrill
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Papers from 1990: Analysis of Animal Carcinogenicity Experiments with Multiple Tumor Types (October 2, 1990) Ying Lu and Hina M. Malani
Summary; Fractional Moments and the Modified Weyl Derivative (October 1, 1990) William J. Redfearn
Summary; Prevalent Cohort Models in Clinical Treatment Studies: An Analysis of Zidovudine Treatment Data (October 1, 1990) Mei-Cheng Wang, Ron Brookmeyer, and Nicholas P. Jewell
Summary; Examination of Effects of Lethality and Mortality Rates on the Tests of Carcinogenicity Using the ED01 Study (August 1, 1990) Hina M. Malani and Ying Lu
Summary; On the Weyl Derivative of Positive Order (August 1, 1990) William J. Redfearn
Summary; Some Surprising Results About Covariate Adjustment in Logistic Regression Models (May 1, 1990) Laurence D. Robinson and Nicholas P. Jewell
Summary; Statistical Analysis of the Time Dependence of HIV Infectivity Based on Partner Study Data (April 1, 1990) Stephen C. Shiboski and Nicholas P. Jewell
Summary; Nonparametric Estimation of the Incubation Period of AIDS Based on a Prevalent Cohort with Unknown Infection Times (April 1, 1990) Peter Bacchetti and Nicholas P. Jewell
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Papers from 1989: Estimating the Incubation Period of AIDS by Comparing Population Infection and Diagnosis Patterns (December 1, 1989) Peter Bacchetti
Summary; Simpson's Paradox: A Graphical Treatment (November 1, 1989) William J. Redfearn
Summary; Random Genetic Mosaics I. Mo