Abstract

In this paper we propose the minimum entropy clustering (MEC) method for clustering genes based on their phylogenetic signals. This entropy based method will cluster two genes together when their concatenation can decrease the entropy. An integral feature of MEC is that it chooses the number of clusters automatically, which is a major advantage over the other methods. Our simulation results show that this method is quite successful in clustering genes with a common phylogeny.

Submitted: March 23, 2007 · Accepted: May 10, 2007 · Published: October 17, 2008

Recommended Citation

Shi, Xiaofei; Gu, Hong; and Field, Chris (2008) "Pattern Classification of Phylogeny Signals," Statistical Applications in Genetics and Molecular Biology: Vol. 7 : Iss. 1, Article 30.
DOI: 10.2202/1544-6115.1289
Available at: http://www.bepress.com/sagmb/vol7/iss1/art30