UT MD Anderson Cancer Center Department of Biostatistics Working Paper Series

Papers from 2008
Practical Model-Based Dose-Finding In Early Phase Clinical Trials: Optimizing tPA Dose For Treatment Of Ischemic Stroke In Children (January 28, 2008) Harry T. Whelan, John D. Cook, Catherine M. Amlie-Lefond, Collin A. Hovinga, Anthony K. Chan, Rebecca N. Ichord, Gabrielle A. deVeber, and Peter F. Thall
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Papers from 2007
Patient-Specific Dose-Finding Based on Bivariate Outcomes and Covariates (December 18, 2007) Peter F. Thall, Hoang Q. Nguyen, and Elihu H. Estey
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The Effect of Population Drift on Adaptively Randomized Trials (December 14, 2007) John D. Cook
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Log-linear Models for Gene Association (October 3, 2007) Jianhua Hu and Valen E. Johnson
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Bayesian inference in semiparametric mixed models for longitudinal data (August 29, 2007) Yisheng Li, Xihong Lin, and Peter Mueller
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Determining the Effective Sample Size of a Parametric Prior (May 13, 2007) Satochi Morita, Peter F. Thall, and Peter Mueller
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A Review of Phase 2-3 Clinical Trial Designs (April 25, 2007) Peter F. Thall
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Accounting for Patient Heterogeneity in Phase II Clinical Trials (April 2, 2007) Jay K. Wathen, Peter F. Thall, John D. Cook, and Elihu H. Estey
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Bayesian and Frequentist Two-Stage Treatment Strategies Based on Sequential Failure Times Subject to Interval Censoring (March 5, 2007) Peter F. Thall, Leiko H. Wooten, Christopher J. Logothetis, Randall E. Millikan, and Nizar M. Tannir
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Comparing Methods of Tuning Adaptively Randomized Trials (January 9, 2007) John D. Cook
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Papers from 2006
Practical Bayesian Adaptive Randomization in Clinical Trials (December 20, 2006) Peter F. Thall and Jay K. Wathen
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Numerical Evaluation of Gamma Inequalities (December 19, 2006) John D. Cook
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Efficacy-Toxicity trade-offs based on Lp norms (December 19, 2006) John D. Cook
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Some Geometric Methods for Constructing Decision Criteria Based On Two-Dimensional Parameters (December 18, 2006) Peter F. Thall
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Understanding the Exponential Tuning Parameter in Adaptively Randomized Trials (December 13, 2006) John D. Cook
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Dose-Schedule Finding in Phase I/II Clinical Trials Using Bayesian Isotonic Transformation (May 4, 2006) Yisheng Li, Benjamin Bekele, Yuan Ji, and John D. Cook
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Bayesian Model Assessment Using Pivotal Quantities (April 12, 2006) Valen E. Johnson
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Bayesian Analysis of Mass Spectrometry Proteomics Data using Wavelet Based Functional Mixed Models (March 23, 2006) Jeffrey S. Morris, Philip J. Brown, Richard C. Herrick, Keith A. Baggerly, and Kevin R. Coombes
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Practical Dose-finding in Phase I Clinical Trials Based on Toxicity Probability Intervals (March 9, 2006) Yuan Ji, Yisheng Li, and Benjamin Bekele
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Bayesian Aggregation Error? (February 20, 2006) Valen E. Johnson
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Bayesian Hypothesis Tests Using Nonparametric Statistics (February 13, 2006) Ying Yuan and Valen E. Johnson
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Papers from 2005
Bayesian Dose-Finding Designs Based on a New Statistical Framework for Phase I Clinical Trials (December 7, 2005) Yuan Ji, Yisheng Li, and Guosheng Yin
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Some Ethical Issues in Phase II Trials in Acute Leukemia (December 7, 2005) Peter F. Thall and Elihu H. Estey
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Monitoring Event Times in Early Phase Clinical Trials: Some Practical Issues (December 7, 2005) Peter F. Thall, Leiko H. Wooten, and Nizar M. Tannir
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Continuous Bayesian adaptive randomization based on event times with covariates (December 7, 2005) Ying Kuen Cheung, Lurdes Y. T. Inoue, J. Kyle Wathen, and Peter F. Thall
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Bayesian Sensitivity Analyses of Confounded Treatment Effects (December 7, 2005) Peter F. Thall and Xuemei Wang
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Bayesian Mixture Models for Complex High-Dimensional Count Data in Phage Display Experiments (December 7, 2005) Yuan Ji, Guosheng Yin, Kam-Wah Tsui, Mikhail G. Kolonin, Jessica Sun, Wadih Arap, Renata Pasqualini, and Kim-Anh Do
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A Geometric Approach to Comparing Treatments for Rapidly Fatal Diseases (December 7, 2005) Peter F. Thall, Leiko H. Wooten, and Elizabeth J. Shpall
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A Hierarchical Model for the Reliability of an Anti-aircraft Missile System (December 6, 2005) C. Shane Reese, Valen E. Johnson, Michael Hamada, and Alyson Wilson
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Penalized Maximum Difference Dose - A New Criterion for Phase I/II Dose-Finding Trials (December 5, 2005) Yuan Ji, Yisheng Li, and Benjamin Bekele
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Bayesian Model Selection Using Test Statistics (November 28, 2005) Jianhua Hu and Valen E. Johnson
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Properties of Bayes Factors Based on Test Statistics (October 26, 2005) Valen Johnson
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A New Dose-Assignment Rule and Bayesian Design in Phase I Oncology Trials (October 17, 2005) Yuan Ji, Yisheng Li, and Benjamin Bekele
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A Note on the Consistency and Interpretation of Bayes Factors Based (June 27, 2005) Valen Johnson
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An Empirical Study of Univariate and GA-Based Feature Selection in Binary Classification with Microarray Data (March 2, 2005) Michael L. Lecocke and Kenneth Hess
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Papers from 2004
Bayes Factors Based on Test Statistics (December 15, 2004) Valen Johnson
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An Empirical Study of Optimism and Selection Bias in Binary Classification with Microarray Data (December 14, 2004) Michael L. Lecocke and Kenneth Hess
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Learning Curves in Classification with Microarray Data (November 29, 2004) Kenneth R. Hess and David L. Gold
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Combining Bayesian Chi-Squared Statistics (November 24, 2004) Valen Johnson
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