Effect of Naga Parpam, a Zinc-Based Siddha Medicine, on Hyperlipidemia in Rats

Ilango Balakrishnan, The New College, Chennai
Dawood Sharief Sultan, The New College, Chennai
Vinoth Kumar Krishnamurthy, The New College, Chennai
Rajkumar Raman, The New College, Chennai
Viswanathan Subramanian, Meenakshi University
Sukumar Ethirajan, Higher College of Technology

Abstract

A zinc-based preparation of Siddha medicine, Naga Parpam (NP), is prescribed in the treatment of a variety of diseases. In folklore practice, NP is added as an ingredient in medicaments to treat obesity. Hence it was studied for antihyperlipidemic activity in cholesterol-fed rats with continuous administration for 30 days in doses of 10 and 20 mg / kg body weight. The drug prevented the elevation of total cholesterol, triglycerides, low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) in serum, liver and heart tissues in a dose-dependent manner when compared to control animals.

Submitted: September 13, 2008 · Accepted: December 31, 2008 · Published: February 3, 2009

Recommended Citation

Balakrishnan, Ilango; Sharief Sultan, Dawood; Krishnamurthy, Vinoth Kumar; Raman, Rajkumar; Subramanian, Viswanathan; and Ethirajan, Sukumar (2009) "Effect of Naga Parpam, a Zinc-Based Siddha Medicine, on Hyperlipidemia in Rats," Journal of Complementary and Integrative Medicine: Vol. 6 : Iss. 1, Article 2.
DOI: 10.2202/1553-3840.1192
Available at: http://www.bepress.com/jcim/vol6/iss1/2

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