Inhibition of Food-Borne Pathogens by T1, a Novel Antimicrobial Peptide as a Potential Food Preservative

Yali Tang, State Key Laboratory of Food Science & Technology, Jiangnan University
Yonghui Shi, State Key Laboratory of Food Science & Technology, Jiangnan University
Wei Zhao, State Key Laboratory of Food Science &Technology, Jiangnan University
Gang Hao, State Key Laboratory of Food Science & Technology, Jiangnan University
Guowei Le, State Key Laboratory of Food Science & Technology, Jiangnan University

Abstract

An efficient and convenient purifying procedure for recombinant peptide was established. Thereby, the aimed antimicrobial peptide T1 containing the conservative sequences derived from cecropin was successfully expressed and purified. The composition of amino acid of the purified peptide T1 was consistent with that of theoretical design. The significant antimicrobial activity of T1 against gram-positive and gram-negative bacteria was demonstrated, suggesting that the conservative sequences in cecropin play an important role in the antimicrobial mechanism and that antimicrobial peptide T1 has the potential to be used as the food preservative.

Submitted: August 24, 2007 · Accepted: May 25, 2008 · Published: June 24, 2008

Recommended Citation

Tang, Yali; Shi, Yonghui; Zhao, Wei; Hao, Gang; and Le, Guowei (2008) "Inhibition of Food-Borne Pathogens by T1, a Novel Antimicrobial Peptide as a Potential Food Preservative," International Journal of Food Engineering: Vol. 4 : Iss. 4, Article 14.
DOI: 10.2202/1556-3758.1287
Available at: http://www.bepress.com/ijfe/vol4/iss4/art14

 
 
 
 

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